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Familial Hibernian Fever
Medications for Tumor Necrosis Factor Receptor Associated Periodic Syndrome
Other names: Familial Hibernian Fever; TNF Receptor Associated Periodic Syndrome; TRAPS
About Tumor Necrosis Factor Receptor Associated Periodic Syndrome: Tumor necrosis factor receptor associated periodic syndrome (TRAPS) is an inheritable autosomal dominant disorder that is characterized by episodes of fevers. The frequency and length of these episodes varies among individuals. As well as Stress associated symptoms are painful conjunctivitis, rash, and nausea, headache, abdominal pain, and joint pain. Patients who develop amyloidosis of the kidney have a worse prognosis compared to other people. TRAPS ISIS caused by a mutation in the TNFRSF1A gene which results in the protein tumor necrosis factor receptor 1 (TNFR1) being faulty) TNFR1 it has a role in signalling and activating apoptosis and inflammation and is cells, yet in TRAPS the faulty TNFR1 is trapped inside the cells and constantly activates inflammation pathways which leads to excessive inflammation.
Drugs Used to Treat Tumor Necrosis Factor Receptor Associated Periodic Syndrome
This set of medications have been utilized in the treating this particular condition, or in some way related to.
| Drug name | Rx / OTC | Pregnancy | CSA | Alcohol | Reviews | Rating | Popularity |
|---|---|---|---|---|---|---|---|
| canakinumab | Rx | C | N | Insert inspection | 0.0 | ||
Generic name: canakinumab systemic Brand name: Ilaris Drug class: interleukin inhibitors For customers: dose, interactions, For specialists: Az Drug Facts, AHFS DI Monograph | |||||||
| Ilaris | Rx | C | N | Insert inspection | 0.0 | ||
Generic name: canakinumab systemic Drug class: interleukin inhibitors For customers: dose, interactions, side effects For professionals: AHFS DI Monograph, Prescribing Information | |||||||
Legend
| Rx | prescription-only |
|---|---|
| OTC | Over the Counter |
| Rx/OTC | Prescription or Over The Counter |
| Off Label | This medication might not be accepted by the FDA for the treatment of this particular condition. |
| Pregnancy Category | |
|---|---|
| A | sufficient and well-controlled studies have failed to demonstrate a risk to the embryo in the first trimester of pregnancy (and there is no evidence of risk in later trimesters). |
| B | Animal reproduction studies have failed to show a risk to the fetus and there are no sufficient and well-controlled studies in pregnant women. |
| C | Animal reproduction studies have shown a negative effect on the fetus and there are no sufficient and well-controlled studies in humans, but possible benefits may warrant used in pregnant women despite potential risks. |
| D | There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but possible benefits may warrant used in pregnant women despite potential risks. |
| X | Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in used in pregnant women clearly outweigh potential benefits. |
| N | FDA have not classified this drug. |
| Controlled Substances Act (CSA) Program | |
|---|---|
| N | isn`t at the mercy of the Controlled Substances Act. |
| 1 | features a higher potential for misuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision. |
| Two | features a higher potential for misuse. Includes a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Psychotherapy can cause severe physical or psychological dependence. |
| 3 | features a potential for abuse less than individuals in schedules 1 and 2 two. Includes a currently accepted medical use in treatment in the United States. Psychotherapy can lead to moderate or low physical dependence or high psychological dependence. |
| 4 | features a very low potential for abuse in accordance with individuals in schedule 3. It`s a currently accepted medical use in treatment in the United States. Psychotherapy can lead to limited physical dependence or psychological dependence. |
| 5 | features a very low potential for abuse in accordance with individuals in schedule 4. Includes a currently accepted medical use in treatment in the United States. Psychotherapy can lead to limited physical dependence or psychological dependence relative to individuals in schedule 4. |
| Infection | |
|---|---|
| X | Interacts with Medication. |
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